ご予約・お問合せはお気軽に TEL:0791-43-5357

〒678-0239
兵庫県赤穂市加里屋30-9

フォトブライト光治療 医療レーザー脱毛 プラセンタ療法 産婦人科 不妊症 ペインクリニック 鍼灸漢方

English Page

MOBILE SITE 上記QRコードよりモバイル専用ページがご覧いただけます。

M&K Health Institute(formerly Fukuda Ladies Clinic)

Welcome to our website

M is from Misao or Moms.

K is from Kiyomi or Kids.

OB/GYN-Infertility-Pain Clinic-Acupuncture-Fotobright-Laser Hair Removal

Director: Misao Fukuda, MD, PhD*
Deputy Director: Kiyomi Fukuda, MD, Phar B, Acup**
M&K Health Institute
*Section of Human Reproductive Health
**Section of Human Health

30-9 Kariya, Ako, Hyogo 678-0239 Japan
Tel: 81-791-43-5357
Fax:81-791-45-1566

Misao Fukuda was born in Hiroshima in 1950. He qualified in 1976 as MD from Kagoshima University Faculty of Medicine and then as PhD from Kobe University Graduate School in 1981. He was Chief at the Department of Obstetrics and Gynaecology in Ako Municipal Hospital, Japan. In 1985 he founded M&K Health Institute (formerly Fukuda Ladies Clinic) with his wife, Kiyomi Fukuda, an anesthesiologist in Ako. Since first meeting with Professor Byskov and Professor Yding Andersen in 1991 he has been involved in collaborative works with them on human follicular growth and atresia. His research interests are follicle and oocyte health in reproductive physiology, obstetric and gynaecological ultrasound and offspring sex ratio in reproductive epidemiology. He has been a visiting professor of Kansai University of Social Welfare since 2012. He has published more than 40 papers and books in Lancet, Fertility Sterility, Human Reproduction etc.

Kiyomi Fukuda was born in Hiroshima in 1950. She qualified in 1973 as Phar. B. from Tohoku University Pharmaceutical Department and then as MD from Hirosaki University School of Medicine in 1980. In 1985 she founded M&K Health Institute (formerly Fukuda Ladies Clinic) with her husband in Ako. She also obtained degree of acupuncture in 2003. Her research interests are comparison of analgesic effectiveness between epidural block and acupuncture on lumbago etc., effect of acupuncture on cerebral infarction and rejuvenation by fotobright. She coauthored more than 30 papers and books in Lancet, Fertility Sterility and Human Reproduction etc.

Bibliography (papers and books)

Fukuda M, Shimizu T, Yding Andersen C. Climate Change, Tohoku earthquake and sex ratio of fetal death & birth. The male to female ratio of newborn infants in Japan in relation to climate change, Tohoku earthquake and fetal deaths. Lap lambert academic publishing 2015, 1-81

Fukuda, M., Fukuda, K., Shimizu, T., Nobunaga M, Mamsen LS, Yding Andersen, C. Climate change is associated with the male to female ratios of fetal deaths and newborn infants in Japan.  Fertil Steril 2014, 102, 1364-1370.

Fukuda M, Fukuda K, Shimizu T, Nobunaga M, Byskov AG, Yding Andersen C. Natural Selection in Utero: Evidence from the Great East Japan Earthquake  Am J Hum Biol 2013, 25, 859

Fukuda M, Fukuda K, Shimizu T, Nobunaga M, Byskov AG, Yding Andersen C.  Maternal smoking during pregnancy and age at menarche of premenopausal and postmenopausal daughters.  Hum Reprod 2012, 28, 551. 

Fukuda, M., Fukuda K, Byskov AG, Yding Andersen C。 Do hormonal characteristics of the luteal phase affect the conception rate of women undergoing IUI treatment in the following menstrual cycle ? Reproductive Biology Insights 2011, 4, 11-15

Fukuda, M., Fukuda K, Shimizu,T.Nobunaga M, Andersen, EW Byskov AG, Yding Andersen C. Reply: No association between age at menarche and sex of offspring   Hum Reprod 2011, 26:3203-4

Fukuda, M., Fukuda K, Shimizu,T.Nobunaga M, Andersen, EW Byskov AG, Yding Andersen C. Reply: The sex ratio of offspring is associated with the mothers’ age at menarche. Hum Reprod 2011, 26, 2589-90.

Fukuda, M., Fukuda K, Shimizu,T.Nobunaga M, Andersen, EW Byskov AG, Yding Andersen C Paternal smoking habits affect the reproductive life span of daughters.    Fertil Steril. 2011, 95, 2542-2544

Fukuda M, Fukuda K, Shimizu T, Nobunaga M, Byskov AG, Yding Andersen C. The sex ratio of offspring is associated with the mothers’ age at menarche. Hum Reprod 2011, 26, 1551-1554.

Humaidan P, Westergaard LG, Mikkelsen AL, Fukuda M, Yding Andersen C. Levels of the epidermal growth factor-like peptide amphiregulin in follicular fluid reflect the mode of triggering ovulation: a comparison between gonadotrophin-releasing hormone agonist and urinary human chorionic gonadotrophin. Fertil Steril. 2011, 95, 2034-2038

Fukuda M, Fukuda K, Tatsumi K, Shimizu T, Nobunaga M, Byskov AG Yding Andersen C.  The ovulation pattern during three consecutive menstrual cycles has a significant impact on pregnancy rate and sex of the offspring Fertil Steril, 2011, 95, 2545-7.

Eilso Nielsen M, Rasmussen IA, Fukuda M, Westergaard LG, Yding Andersen.  Concentration of Anti-Mullerian Hormone in fluid fromsmall antral follicles show a negative correlation with CYP19 mRNA expression in the corresponding granulosa cells.  Mol Hum Reprod 2010, 16, 637-43.

Fukuda M, Fukuda K, Yding Andersen C and Byskov AG.  Ovulation jumping from the left to the right ovary in two successive cycles may increase the chances of pregnancy during intrauterine insemination and/or in vitro fertilization natural cycles.  Fertil. Steril., 2006, 85: 514-7.

Fukuda, M., Fukuda, K., Yding Andersen, C., and Byskov, A.G.  Basal oestradiol and the ratios of oestradiol/androgens and oestradiol/FSH reflect pregnancy potential of women receiving IUI during natural cycles?  Reprod Biomed Online. 2003, 6, 452-55.

Fukuda, M., Fukuda, K., Shimizu, T., Yding Andersen, C., and Byskov, A.G.  Periconceptional smoking and the male to female ratio in the offspring-re-assessment of a recently proposed hypothesis.  Int J Epidemiol,.2003, 32, 470-471.

Hashimoto, K., Shimizu, T., Fukuda, M., Ozaki, M., Shimoya, K., Koyama, M. and Murata, Y. Pregnancy Outcome of Embryonic/Fetal Pleural Effusion in the First Trimester.  J. Ultrasound Med.  2003, 22, 501-505.

Fukuda, M., Fukuda, K., Shimizu, T., Yding Andersen, C., and Byskov, A.G.  Periconceptual parental smoking and sex ratio of offspring.  Lancet, 2002, 360, 1515-1516.

Fukuda, M., Fukuda, K., Shimizu, T., Yding Andersen, C., and Byskov, A.G.  Parental periconceptional smoking and male:female ratio of newborn infants.  Lancet, 2002, 359, 1407-1408.

Fukuda, M., Fukuda, K., Yding Andersen, C. and Byskov, A. G.Characteristics of human ovulation in natural cycles correlated to age and achievement of pregnancy.  Hum. Reprod., 2001, 16, 2501-2507.

Fukuda, M., Fukuda, K., Yding Andersen, C. and Byskov, A. G.  Side of ovulation, hormones and sex ratio.  Hum. Reprod., 2001, 16, 198-199.

Fukuda, M., Fukuda, K., Yding Andersen, C. and Byskov, A. G.  Right-sided ovulation favours pregnancy more than left-sided ovulation.  Hum. Reprod., 2000, 15, 1921-1926

Fukuda, M., Fukuda, K., Yding Andersen, C. and Byskov, A. G. Does anovulation induced by oral contraceptives favor pregnancy during the following two menstrual cycles?  Fertil. Steril., 2000, 73, 742-747.

Yding Andersen, C., Morineau, G., Fukuda, M., Westergaard, L.G., Ingerslev, H.J., Fiet, J. and Byskov, A.G.   Assessment of the follicular cortisol:cortisone ratio.  Hum. Reprod., 1999, 14, 1563-1568.

Fukuda, M., Fukuda, K., Yding Andersen, C. and Byskov, A. G. Anovulations in an ovary during two menstrual cycles enhance the pregnancy potential of oocytes matured in that ovary during the following third cycle.  Hum. Reprod., 1999, 14, 96-100.

Fukuda, M. and Fukuda, K.  Endometrial and endometrial cavity movement in ART.  In Allahbadia, G. (ed), Transvaginal sonography in infertility.  Rotunda Medical Technologies, Bombay, 1998, 522-529.

Fukuda, M., Fukuda, K., Shimizu, T. and Moller H.  Decline in sex ratio at birth after Kobe earthquake.  Hum. Reprod., 1998, 13, 2321-2322

Fukuda, M., Fukuda, K., Yding Andersen, C. and Byskov, A. G.  Contralateral ovulation shortens follicular phase length and favours pre-embryo development during ovarian stimulation with clomiphene citrate.  Hum. Reprod., 1998, 13, 1590-1594.

Fukuda, M. and Fukuda, K.  Uterine endometrial cavity movement and cervical mucous.  In Allahbadia, G. (ed), Endosonography in Obstetrics and Gynaecology.  Rotunda Medical Technologies, Bombay, 1997, 532-537.

Fukuda, M. and Fukuda, K.  A simplified in-vitro fertilization (IVF) using disposable materials.  Hum. Reprod., 1997, 12, 2588-2590.

Fukuda, M., Fukuda, K., Yding Andersen, C. and Byskov, A. G.  Does corpus luteum locally affect follicular growth negatively?  Hum. Reprod., 1997, 12, 1024-1027.

Fukuda, M., Fukuda, K., Yding Andersen, C. and Byskov, A. G.  Contralateral selection of dominant follicle favours pre-embryo development.  Hum. Reprod.,1996, 11, 1958-1962.

Fukuda, M., Fukuda, K. and Ranoux, C.  Unexpected low oxygen tension of intravaginal culture.  Hum. Reprod., 1996, 11, 1293-1295

Fukuda, M., Fukuda, K., Shimizu, T., Yomura, W. and Shimizu, S.  Kobe earthquake and reduced sperm motility.  Hum. Reprod., 1996, 11, 1244-1246.

Fukuda, M., Fukuda, K., Yding Andersen, C. and Byskov, A. G.  Healthy and atretic follicles: vaginosonographic detection and follicular fluid hormone profiles. Hum. Reprod., 1995, 10, 1633-1637.

Fukuda, M. Fukuda, K.  Uterine endometrial cavity movement and cervical mucous.  Hum. Reprod., 1994, 9, 1013-1016.

Fukuda M., Shimizu T., Fukuda K., Yomura W., and Shimizu S.   Transvaginal hysterosonography for differential diagnosis between submucous and intramural myoma.  Gynecol. Obstet. Invest., 1993, 35, 236-239.

Fukuda M, Fukuda K, Shimizu T, Natsuyama E, Mochizuki M.  Two types of translucent membrane of caesarean section scar tissue.  Lancet, 1992, 339, 254-255.

Fukuda M, Shimizu T, Ihara Y, Fukuda K, Natsuyama E, Mochizuki M. Ultrasound examination of caesarean section scars during pregnancy.  Arch Gynecol Obstet., 1991, 248 : 129-138.

Fukuda M, Fukuda K, and Mochizuki M.  Examination of previous caesarean section scars by ultrasound.  Arch Gynecol Obstet.,1988, 243 : 221-224.

Fukuda, M., Katayama, K., Tsujimoto, D., Akahori, T. and Tojo, S. Inhibitory effect of corpus luteum on follicular growth and induced superovulation in immature rats.  Jap. J. Fertil. Steril.,1983,  28, 45-49.

Fukuda, M., Katayama, K. and Tojo, S. Inhibitory effect of progesterone on follicular growth and induced superovulation in the rat.  Arch. Gynecol., 1980, 230,77-87.

Presentations in international scientific meetings

Fukuda M, Tsujimoto D, Katayama K and Tojo S.  Inhibition of follicular growth and induced superovulation by exogenous progesterone in immature rats.  Tenth World Congress on Fertility and Sterility, Madrid, July 9th, 1980.

Tsujimoto D, Fukuda M, Katayama K and Tojo S.  Scanning electron microscopic studies on stigmas in rat ovaries.  Tenth World Congress on Fertility and Sterility, Madrid, July 9th, 1980.

Fukuda M, Katayama K, Tsujimoto D and Mochizuki M.  Interfering effect of corpus luteum on follicular growth and induced superovulation in immature rats.  Ninth Asia & Oceanic Congress of Obstetrics and Gynecology, Seoul, South Korea, Sept. 4-9, 1983.

Fukuda M, Shimizu T, Ihara Y, Fukuda K, Natsuyama E, Mochizuki M.  Ultrasonographic observation of previous cesarean section scar -vaginal delivery or repeat cesarean section-. Fifth meeting of World Federation for Ultrasound in Medicine and Biology, Washington, D.C., Oct. 17-21, 1988.

Fukuda M, Shimizu T, Fukuda K, Natsuyama E and Mochizuki M.  New ultrasound examination of previous caesarean section scars during pregnancy, labor and postpartum.  Sixth meeting of World Federation for Ultrasound in Medicine and Biology, Copenhagen, Sept. 1-6, 1991.

Fukuda M, Fukuda K, Katayama K, Mochizuki M, Yding Andersen C and Byskov A G.  Preovulatory and atretic follicles: ultrasound detection and follicular fluid hormone profiles.  Eighth World Congress on In Vitro Fertilization and Alternate Assisted Reproduction, Kyoto, Sept. 12-15, 1993.

Fukuda M, Fukuda K, Yding Andersen C and Byskov A G.  Dominant follicular health and pregnancy outcome in contralateral versus ipsilateral ovulation.  Twelfth Annual Meeting of the ESHRE (European Society of Human Reproduction and Embryology), Maastricht, June 30-July 3, 1996.

Fukuda M, Fukuda K, Yding Andersen C and Byskov A G.  Inter&intra-ovarian control mechanisms that influence oocyte quality and pregnancy potential.  Thirteenth International Workshop on the Development and Function of the Reproductive Organs.  Copenhagen June 12-15, 2004.

Fukuda M, Fukuda K, Tatsumi K, Shimizu T, Nobunaga M, Byskov AG Yding Andersen C.  Does the ovulation pattern in consecutive menstrual cycles affect the sex ratio of subsequent conceived children?  6th Workshop on mammalian folliculogenesis and oogenesis: from basic science to the clinic. Potsdam Germany October 8-10, 2009.
PAGE TOP